Immunoperoxidase anti-keratin staining of epidermal and pilar cysts

July 1984 in “ British Journal of Dermatology ”

D.W.K. Cotton, N Kirkham, Brian J. Young

TLDR Epidermal cysts come from the skin, while pilar cysts come from hair follicles.

The study conducted on epidermal and pilar cysts used anti-keratin antibodies derived from human hair and callus to stain the cysts. The results showed distinct staining properties between the two types of cysts, which supported the hypothesis that epidermal cysts originated from the epidermis, while pilar cysts originated from the trichilemmal layer of the hair follicle.

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