Immunofluorescence analysis of the basement membrane zone components in human anagen hair follicles
July 2003
in “
Experimental Dermatology
”
Research cited in this study
2 / 2 resultsresearch Expression of Basement Membrane Proteins and Interstitial Collagens in Dermal Papillae of Human Hair Follicles
research Heterotypic Cell Contacts and Basal Lamina Morphology During Hair Follicle Development in the Mouse: A Light, Scanning, and Electron Microscopic Study at the Site of Tissue Interaction
Heterotypic cell contacts likely help hair matrix cells differentiate during mouse hair follicle development.
Related Research
2 / 2 resultsresearch Immunofluorescence analysis of the basement membrane zone components in human anagen hair follicles
research Ultrastructural Study on Connective Tissue-Epithelial Junctions in Anagen Hair Follicle of Human Fetus
This study examined the ultrastructural differences in connective tissue-epithelial junctions in anagen hair follicles of human fetal scalp skin. It found that the junctions around the dermal papilla and on the outside of the hair follicle differed significantly from those in the dermoepidermal junction of the skin. Notably, structures such as hemidesmosomes, tonofilaments, attachment plaques, sub-basal dense plates, and anchoring filaments, which were present in the skin, were absent in the dermal papilla. The basal lamina was smoother, and collagen fibers were orthogonally arranged on the outside of the hair follicle, unlike in the dermal papilla. These findings suggested that the mechanical connection between the hair follicle and connective tissue was weaker than in the skin, reflecting the dynamic nature of the anagen phase compared to the stable state of the epidermis.