Hyperprolactinemia in Patients with High TSH Levels with Both Clinical and Subclinical Hypothyroidism

    April 2022 in “ PANACEA JOURNAL OF MEDICAL SCIENCES ”
    Jyotindra Kumar Sahu, M Ravikant, A. K. Thakur
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    TLDR People with both obvious and not-so-obvious underactive thyroid issues often have higher levels of the hormone prolactin.
    The study "Hyperprolactinemia in patients with high TSH levels with both clinical and subclinical hypothyroidism" involved 138 patients with thyroid-related issues. The research found that serum prolactin levels were significantly increased in both subclinical (28.7 ± 6.4 ng/mL) and clinical hypothyroidism (15.02 ± 4.2ng/mL) compared to controls. Hyperprolactinemia was observed in 22.9% of patients with subclinical hypothyroidism and 8.3% of patients with clinical hypothyroidism. The study concluded that prolactin regulation is altered in patients with both clinical and subclinical hypothyroidism, suggesting that thyroid function tests should be conducted in patients with hyperprolactinemia before performing further tests.
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      community does lowering your prolactin levels regrow hair?

      in Research/Science  9 upvotes 2 years ago
      The potential of lowering prolactin levels to regrow hair, with a reference to Bayer's drug HMI 115 which has been indicated as having this effect. Treatments mentioned include Minoxidil and Finasteride, as well as RU58841.

      community how about progesterone cream?

      in Research/Science  22 upvotes 9 months ago
      Progesterone cream might help with hair loss by inhibiting DHT production and suppressing prolactin, which can increase DHT. Some dermatologists have used progesterone for hair loss treatment, and it has been effective, sometimes combined with minoxidil, finasteride, and hydrocortisone.

      community hmi115 is coming. Prepare yourselves for what's coming

      in Technology  108 upvotes 1 year ago
      The conversation discusses HMI-115, a potential cure for hair loss. Users share mixed opinions, with some expressing skepticism and others sharing anecdotal evidence of its effectiveness, including photos of significant hair regrowth from a trial participant.

      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  39 upvotes 2 years ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

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