Human Skin is a Steroidogenic Tissue: Steroidogenic Enzymes and Cofactors Are Expressed in Epidermis, Normal Sebocytes, and an Immortalized Sebocyte Cell Line (SEB-1)

May 2003 in “ Journal of Investigative Dermatology ”

Diane Thiboutot, K. Gilliland, Zhaoyuan Cong, S. Jabara, Jan M. McAllister, Aruntha Sivarajah, Gary A. Clawson

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research Corticotropin-releasing hormone: An autocrine hormone that promotes lipogenesis in human sebocytes

284 citations , May 2002 in “Proceedings of the National Academy of Sciences”

CRH promotes fat production in skin cells, affecting conditions like acne.

research Sebocytes Are the Key Regulators of Androgen Homeostasis in Human Skin

196 citations , May 2001 in “The journal of investigative dermatology/Journal of investigative dermatology”

Sebocytes play a key role in controlling androgen levels in human skin.

research Immunohistochemical Localization of Types 1 and 2 5α-Reductase in Human Scalp

100 citations , September 1999 in “British Journal of Dermatology”

The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.