Aging of the Human Lip: Current Knowledge and Clinical Implications

    Fanghui Sun, Yue Liu, Tao Zhang
    TLDR Lip aging differs from facial aging, needing specific care for barrier, wrinkles, and pigment changes.
    The review highlights that lip aging is distinct from facial aging due to differences in barrier function, melanin content, and other physiological factors. Women tend to exhibit more perioral wrinkles than men. Effective anti-aging strategies for lips should focus on barrier restoration, mild anti-aging methods, and photoaging prevention for the vermilion, while perioral aging should be addressed by preventing ECM degradation and enhancing tissue volume. Recognizing gender differences and managing pigmentary changes are crucial for developing targeted anti-aging lip products.
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