Histocompatibility and Long-Term Results of Follicular Unit-Like Wigs After Xenogeneic Hair Transplantation: An Experimental Study in Rabbits

    April 2011 in “ ISRN Dermatology (Print) ”
    Yu Sun, Feng Lu, Ge Liu, Zhidan Zhang, Zijie Zhang, Zhexiang Fan
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    TLDR The wigs made from human hair and polypropylene were mostly well-tolerated and durable in rabbits, suggesting they could be a new option for people with extensive hair loss.
    In 2011, researchers tested the compatibility and durability of follicular unit-like wigs made from human hair and polypropylene by transplanting them into 12 New Zealand rabbits. The wigs were well-tolerated, with only mild and decreasing inflammation observed, and no significant hair degradation. The wigs integrated well with the rabbits' tissue, showing an increase in collagen fibers and stable integration over the one-year study period. The loss rate of the wigs was low at 4.1 ± 4.0%, and the wigs maintained a satisfactory appearance. The study concluded that these wigs have potential for industrial production and could provide a new option for patients with extensive alopecia, without the need for traditional hair follicle extraction.
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