Endogenous Production of Heparin-Binding EGF-Like Growth Factor During Murine Partial-Thickness Burn Wound Healing

    March 2002 in “ Journal of Burn Care & Rehabilitation ”
    Randolph K. Cribbs, Paul A. Harding, Mark Luquette, Gail E. Besner
    TLDR HB-EGF and TGF-α help heal burns by boosting skin cell growth.
    The study investigated the role of heparin-binding EGF-like growth factor (HB-EGF) and transforming growth factor-alpha (TGF-α) in healing murine partial-thickness scald burns. It was found that the expression of HB-EGF mRNA and the production of HB-EGF and TGF-α proteins peaked on the fifth day post-burn, aligning with the highest rate of keratinocyte proliferation. This suggested that HB-EGF and TGF-α worked together to enhance wound healing after thermal injury by promoting epithelial cell growth and keratinocyte proliferation.
    Discuss this study in the Community →

    Related Community Posts Join

    5 / 5 results

      community Going to start the sulforaphane experiment

      in Treatment  15 upvotes 4 years ago
      A user shared their experience with hair loss treatments, including minoxidil and finasteride, and their negative side effects. They outlined a new treatment plan involving microneedling, various supplements, minoxidil foam, ketoconazole shampoo, and an anti-inflammatory diet, with plans to document progress over three months. Another user responded, indicating their own similar efforts were a waste of money.

      community Correct way to microneedling, with existent hair

      in Microneedling  12 upvotes 1 year ago
      The conversation discusses the correct method of microneedling for hair loss, questioning whether it should be done on areas with long hair without risking hair damage, and if it's necessary for improving blood flow to existing hair. No specific treatments were mentioned.

    Related Research

    1 / 1 results