[Genetic and biochemical aspects of keratin synthesis by hair follicles].

    April 2007 in “ PubMed ”
    I A Makar, V. V. Havryliak, H. M. Sedilo
    TLDR Coordinated gene activities are crucial for normal hair growth.
    This review article summarized the genetic and biochemical aspects of keratin synthesis by hair follicles, highlighting the importance of coordinated gene activities for hair follicle matrix cell differentiation and normal hair growth. It was found that keratin genes are organized in clusters, typically 5-10 kb in size, within the genome. Two keratin intermediate filament (IF) gene families and five keratin-associated protein (KAP) gene families were identified, with some clusters mapped. The proximity of these clusters suggested that "global" regulatory domains might control their expression.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 153 results

      community Results of Procyanidin B2 in clinical studies

      in Treatment  11 upvotes 5 years ago
      Procyanidin B2, a compound derived from Annurca apples, as a potential treatment for pattern hair loss. Several clinical studies were mentioned, which found that procyanidin B2 could increase hair growth, density, and keratin content. Other treatments such as Minoxidil, Finasteride, and RU58841 were not discussed.

      community Summary of Procapil video by Haircafe

      in Minoxidil  2 upvotes 3 months ago
      Procapil is marketed as a natural hair loss treatment but lacks strong evidence and is industry-biased. Minoxidil and Finasteride are the only FDA-approved treatments for androgenetic alopecia.

      community Nice product I discovered, thought I would share.

      in Treatment  456 upvotes 6 months ago
      A product that makes hair look thicker and healthier without promoting regrowth. Discussions include treatments like minoxidil, finasteride, red light therapy, and a serum with caffeine and peptides, with mixed effectiveness opinions.

      community Are carbohydrates needed for hair growth

      in Research/Science  26 upvotes 1 year ago
      A 47-year-old male experienced significant hair loss after losing 37 kg in 6 months on a low-carb diet and started taking biotin, zinc, iron, selenium, and spectral dcn-n. Replies suggest that while carbs are not directly needed for hair growth, they help regulate hormones and nutrient absorption, and rapid weight loss can also contribute to hair loss.

      community The truth about Dutasteride (w/ sources)

      in Finasteride/Dutasteride  52 upvotes 2 years ago
      The effectiveness of Dutasteride compared to Finasteride in treating hair loss, with evidence given such as studies and experiences, as well as discussion around whether one should switch from Finasteride to Dutasteride. There is also a discussion on post-Dutasteride syndrome.

    Related Research

    2 / 2 results