Formononetin: A Pathway to Protect Neurons

Formononetin (FMN), a phytoestrogen from the flavonoid family, exhibited significant neuroprotective properties, making it a promising candidate for drug development targeting the central nervous system. It showed potential in preventing and treating neurological diseases such as traumatic brain injury, spinal cord injury, ischemic stroke, cerebral ischemia-reperfusion, Alzheimer’s disease, and nerve tumors. The study highlighted FMN's pharmacological effects, including antioxidative, antihypertensive, antitumor, and anti-infective properties, and explored its signaling pathways for neuroprotection.