Follicular miniaturization in female pattern hair loss: clinicopathological correlations
November 2006
in “British Journal of Dermatology”
TLDR Hair loss severity relates to increased miniaturization in female pattern hair loss.
This study examined the relationship between hair loss severity and follicular miniaturization in female pattern hair loss (FPHL). Biopsies were taken from 42 women with varying degrees of hair loss, and the number of hair follicles, terminal follicles, and vellus-like follicles were assessed. The results showed that the absolute number of vellus follicles increased with advancing hair loss, indicating that follicular miniaturization does occur in FPHL. The study also suggested that miniaturization is a dynamic process that eventually progresses to follicular deletion. The researchers suggest that the terminal/vellus ratio can be used as a histological marker of female pattern hair loss.
View this study on academic.oup.com →
Cited in this study
research The reliability of horizontally sectioned scalp biopsies in the diagnosis of chronic diffuse telogen hair loss in women
Horizontally sectioned scalp biopsies are more reliable for diagnosing hair loss in women when three samples are taken instead of one.
research Women who present with female pattern hair loss tend to underestimate the severity of their hair loss
Women with female pattern hair loss often underestimate how severe it is.
research Hair density, hair diameter and the prevalence of female pattern hair loss
FPHL affects hair density and diameter, causing visible hair loss in older women.
research Measuring Reversal of Hair Miniaturization in Androgenetic Alopecia by Follicular Counts in Horizontal Sections of Serial Scalp Biopsies: Results of Finasteride 1mg Treatment of Men and Postmenopausal Women
Finasteride 1mg helps reverse hair miniaturization in men and postmenopausal women.
research Chronic telogen effluvium: Increased scalp hair shedding in middle-aged women
Middle-aged women with chronic telogen effluvium experience increased hair shedding but usually don't get significantly thinner hair.
research Diagnostic and predictive value of horizontal sections of scalp biopsy specimens in male pattern androgenetic alopecia
Horizontal scalp biopsy sections effectively diagnose and predict MPAA, with follicular density and inflammation impacting hair regrowth.
Related
research Hair Loss and Hirsutism Management
Low-level light therapy, possibly combined with other treatments, may become a leading hair loss treatment, while hirsutism often worsens with age and lacks preventive options.
research Hair loss (alopecia or baldness)
Baldness is often hereditary and linked to male hormones, becoming noticeable when half the hair is lost.
research Changes in the sebaceous gland in patients with male pattern hair loss (androgenic alopecia)
Sebaceous glands in male pattern hair loss patients have more lobules and might cause early hair growth phase shifts.
research Hair loss in women: medical and cosmetic approaches to increase scalp hair fullness
Female pattern hair loss can be treated with medications, surgery, and cosmetic products, considering its psychological impact.
research Occipital involvement in female pattern hair loss: histopathological evidences
Occipital scalp affects female hair loss; terminal/vellus ratio helps diagnose androgenetic alopecia.
research Follicular miniaturization in female pattern hair loss: clinicopathological correlations
Hair loss severity relates to increased miniaturization in female pattern hair loss.
