Fluridil, a Rationally Designed Topical Agent for Androgenetic Alopecia
August 2002
in “Dermatologic Surgery”
TLDR
Fluridil safely promotes hair growth in men with androgenetic alopecia.
The study evaluated the safety and efficacy of topical fluridil in treating androgenetic alopecia (AGA) in men. The study found that fluridil is safe, non-irritating, and effective in promoting hair growth by increasing the anagen:telogen ratio. The increased ratio was achieved within the first 3 months and remained for 9 months, making fluridil a promising agent for the management of incipient or recent male AGA. However, further studies are needed to assess fluridil's safety and effectiveness in female AGA and hirsutism.
View this study on journals.lww.com →
Cited in this study
research Changes in hair weight and hair count in men with androgenetic alopecia after treatment with finasteride, 1 mg, daily
Finasteride increases hair weight and count in men with hair loss.
research Changes in hair weight and hair count in men with androgenetic alopecia, after application of 5% and 2% topical minoxidil, placebo, or no treatment
Minoxidil increases hair weight and count temporarily in men with hair loss.
research A controlled study of the effects of RU58841, a non-steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone-conditioned nude mice
research Preliminary pharmacokinetics and metabolism of novel non-steroidal antiandrogens in the rat: Relation of their systemic activity to the formation of a common metabolite
Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.
research RU 58841, a new specific topical antiandrogen: A candidate of choice for the treatment of acne, androgenetic alopecia and hirsutism
RU 58841 may treat acne, hair loss, and excessive hair growth.