Finasteride: Middle-Age Cure-All for Alopecia and Benign Prostatic Hyperplasia? – Reply – I

The document discussed the effects of finasteride on androgenetic alopecia and prostate cancer, addressing concerns about an increased incidence of high-grade prostate cancer in finasteride users. It was noted that 37% of prostate cancer cases in the finasteride group had Gleason scores of 7 or more, compared to 22% in the placebo group. However, studies suggested that this was not due to finasteride inducing cancer but possibly due to histological changes affecting grading. Finasteride was shown to reduce prostate volume by 30%, which could increase tumor detection rates. Despite initial concerns, the data indicated that finasteride was effective for hair loss and had potential in prostate cancer prevention without increasing high-grade cancer risk.