Epidermal Field Carcinogenesis in Bald-Headed: An Attempt at Fine-Tuning Early Non-Invasive Detection

April 2009 in “ Oncology Reports ”

Piérard

epidermal field carcinogenesis bald-headed non-invasive detection actinic changes ultraviolet light-enhanced visualization photoaging mosaic melanoderma keratinocyte dysplasia skin cancer UV light

TLDR Bald-headed individuals may need early non-invasive detection for skin changes linked to cancer risk.

The study investigated epidermal field carcinogenesis in bald-headed men, focusing on early non-invasive detection of actinic changes on the scalp. Using ultraviolet light-enhanced visualization, 50 healthy men over 50 years old with long-term baldness were examined for photoaging-associated changes. The study identified faint mosaic melanoderma (FMM) and atypical scaliness on the scalp, which were not present on the forehead. These changes, distinct from common scalp conditions, suggested a potential link to actinic field carcinogenesis and early keratinocyte dysplasia. The findings highlighted previously undescribed skin surface changes in early balding, indicating a need for further investigation into their role in skin cancer development.

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