Efficacy of systemic minoxidil and tofacitinib combination in treatment‐resistant alopecia universalis
June 2021
in “Journal of Cosmetic Dermatology”
TLDR Using minoxidil and tofacitinib together can effectively treat severe hair loss.
The document presents a case study of a 31-year-old male patient with treatment-resistant alopecia universalis (AU), a severe form of hair loss. The patient was successfully treated with a combination of tofacitinib and oral minoxidil after other treatments failed to show results. The patient's Severity of Alopecia Tool Score (SALT) improved from 100 to 35 after the treatment. The study concludes that the combination of tofacitinib and oral minoxidil may be an effective alternative treatment approach in severe alopecia areata (AA) cases. However, it suggests that further studies are necessary to confirm this result.
View this study on onlinelibrary.wiley.com →
Cited in this study
research Combination tofacitinib and oral minoxidil treatment for severe alopecia areata
Tofacitinib and oral minoxidil together effectively regrow hair in severe alopecia areata patients.
research Minoxidil for patchy alopecia areata: systematic review and meta‐analysis
Minoxidil effectively and safely treats patchy hair loss, but more research needed.
research Alopecia areata
Some treatments can help with a hair loss condition called alopecia areata, but none ensure lasting results; choices depend on the person, with JAK inhibitors showing promise for severe cases.
research Treatment of Alopecia Areata With Tofacitinib
Tofacitinib helped regrow hair in people with severe alopecia, but side effects occurred and benefits stopped after treatment ended.
research Tofacitinib for the treatment of severe alopecia areata and variants: A study of 90 patients
Tofacitinib is effective and safe for severe hair loss, but full regrowth is less likely after 10 years of hair loss.
research Alopecia areata update
Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.
Related
research Androgenetic alopecia in adolescents.
research Disorders of the Hair and Scalp in Children
The document concludes that various hair and scalp disorders in children have specific treatments and proper diagnosis is essential.
research Common hair disorders.
The article described symptoms and treatments for four common hair problems but didn't give detailed information.