Effects of testosterone, dihydrotestosterone and estradiol on growth of human hair outer root sheath keratinocytes in vitro

    Franklin Kiesewetter, Akira Arai, Jutta v. Hintzenstern, H. Schell
    TLDR Testosterone, DHT, and estradiol significantly affect hair cell growth.
    The study investigated the effects of testosterone, dihydrotestosterone (DHT), and estradiol on the growth of human hair outer root sheath keratinocytes in vitro. The research aimed to understand how these hormones influenced hair growth at the cellular level. The findings suggested that these hormones played a significant role in regulating the growth of keratinocytes, which are crucial for hair development. The study provided insights into the hormonal regulation of hair growth, which could have implications for understanding conditions like androgenetic alopecia. However, the document did not specify the number of participants or detailed experimental results.
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