The Effectiveness of Fermented Wheat Germ Extract as an Adjunct Therapy in the Treatment of Cancer: A Systematic Review

The document reviewed the potential of fermented wheat germ extract (FWGE), specifically Avemar, as an adjunct therapy in cancer treatment. While Avemar showed promising results in laboratory and animal studies by promoting apoptosis of cancer cells, starving cancer cells of sugar, enhancing immune targeting, and preventing abnormal cell repair, human trials were limited in scale. These trials suggested that Avemar might help decrease disease progression, enhance conventional treatments, improve quality of life, and reduce side effects. However, despite encouraging early evidence, the clinical effectiveness of Avemar as an adjunctive cancer therapy had not been conclusively established.