TLDR Finasteride significantly reduces prostate cancer risk.
The Prostate Cancer Prevention Trial, which included approximately 18,000 men aged 55-70 years, investigated the effects of finasteride (Proscar) on prostate cancer risk. The study found an overall reduction in prostate cancer risk of about 25% when considering all biopsies and about 10% for "for cause" biopsies. After adjusting for the decrease in prostate size due to finasteride, the analysis by Kaplan et al. identified a reduction of about 50% for Gleason score 6 cancer and 20% for Gleason score 7 cancer. These findings suggested a significant impact of finasteride on reducing prostate cancer risk.
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December 2006 in “Lancet Oncology” Finasteride significantly reduces PSA levels in men, and doctors should adjust PSA readings for those taking the drug.
Saw palmetto extract is effective and safe for treating lower urinary tract symptoms, working as well as certain medications, and works even better in severe cases.
23 citations
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June 1999 in “Clinical Therapeutics” Finasteride is a cost-effective option for treating BPH, reducing risk of urinary issues and surgery.
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October 1994 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride increases hair growth, prolongs hair cycle, and lowers dihydrotestosterone levels.
5 citations
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November 1994 in “BMJ” Merck will refund the cost of the drug finasteride if it doesn't improve symptoms within six months or if the patient needs surgery within two years.
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