Knowledge Mapping of Drug Repositioning's Theme and Development

The document analyzes drug repositioning, which finds new uses for existing drugs, highlighting its role in speeding up drug development and cutting costs. Using bibliometric tools, the study examined 3,814 documents, identifying the U.S., China, and India as leaders in the field. Notable repositioned drugs include Sildenafil and Minoxidil. The study emphasizes the impact of SARS-CoV-2 on research trends, with most top-cited articles related to the virus, and highlights the use of bioinformatics and deep learning in drug discovery. Drug repositioning extends beyond viral infections to diseases like cancer and osteoporosis, with pathways such as serendipitous discoveries. Challenges include patenting issues and funding needs, and future research should integrate clinical data and explore repositioning's potential further.