Structural Elements of DNA and RNA Eukaryotic Expression Vectors for In Vitro and In Vivo Genome Editor Delivery

    December 2022 in “ Molecular Biology
    AA Zagoskin, Maria V. Zakharova, Maxim Nagornykh
    The document reviews the structural elements of nonviral DNA- and RNA-based expression vectors used for gene editing and their delivery methods both in vitro and in vivo. It highlights the importance of effective delivery and expression of gene editors in cells and tissues for therapeutic applications in healthcare and agriculture. The paper discusses the use of both virus-based and nonviral systems for successful gene editor delivery, addressing the challenges associated with safe and effective therapeutic use of gene editing technologies.
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