Influence of Dietary Linoleic Acid (18:2, N6) on the Effects of Hyperthyroidism in Mus Musculus

This study explored the potential of dietary linoleic acid (18:2, n6) to mitigate the effects of hyperthyroidism in Mus musculus, inspired by Ershoff's 1949 findings that a soybean meal diet counteracted hyperthyroidism symptoms like weight loss and hair loss in rats. While previous research indicated that unsaturated fatty acids might inhibit thyroid hormone binding and increase free hormone levels in plasma, this study aimed to investigate if polyunsaturated fatty acids could offer a dietary treatment for hyperthyroidism, a common endocrine disorder.