Influence of Dietary Linoleic Acid (18:2, N6) on the Effects of Hyperthyroidism in Mus Musculus
January 1992
in “
Research Online (University of Wollongong)
”
New to Linoleic Acid? There is a guide in the encyclopedia. Read the guide → Studysummary This investigation reviews the potential impact of polyunsaturated fatty acids on thyroid hormone action and does not report new results, highlighting a need for further research on dietary treatment for hyperthyroidism.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
This study, conducted by Nalini Deshpande, was inspired by earlier research indicating that a diet high in full-fat soybean meal could mitigate some physical effects of hyperthyroidism, such as weight loss and hair loss, in rats. However, this diet did not affect the increased oxygen consumption associated with thyroid hormone treatment. Subsequent research suggested that unsaturated fatty acids might inhibit thyroid hormone binding to the nucleus and reduce their binding to plasma proteins, potentially increasing free hormone levels in the plasma. The study aimed to explore whether polyunsaturated fatty acids could influence thyroid hormone action as a potential dietary treatment for hyperthyroidism, a common endocrine disorder.
