Concurrent Lichen Planopilaris and Female Androgenic Alopecia in Skin of Color: A Case Series

    March 2025 in “ PubMed ”
    Eliza Balazic, Hailey Konisky, Eden Axler, Kseniya Kobets
    TLDR Thorough scalp exams are crucial for diagnosing hair loss conditions in people with skin of color.
    This case series highlights the importance of comprehensive scalp examination in diagnosing concurrent lichen planopilaris (LPP) and female androgenic alopecia (FAGA) in individuals with skin of color. The study involved three cases, where trichoscopy and biopsies were used to differentiate between FAGA and LPP. Findings showed that while the temporal scalp exhibited signs of FAGA, the frontal scalp showed characteristics of scarring alopecia indicative of LPP. All patients were treated with clobetasol 0.05% solution and minoxidil 5% foam/solution for FAGA, and intralesional triamcinolone acetonide for LPP. The report underscores the necessity of total scalp dermoscopy and targeted biopsies for accurate diagnosis and treatment planning.
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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 7 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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      in Chat  10 upvotes 4 months ago
      The user has been using finasteride, minoxidil, and nizoral for hair loss but hasn't seen regrowth, only maintenance. They are considering switching to dutasteride, which is believed to be more effective, but are concerned about potential side effects.

      community How essential is scalp biopsy when dealing with hair loss?

      in Treatment  6 upvotes 4 months ago
      The user experienced hair loss despite using Fin and Min for 12 years and switched to Dutasteride, RU58841, and Keto scalp serum, but shedding and itch persist. They are considering increasing Dutasteride to 2.5mg and questioning the necessity of a scalp biopsy, with mixed opinions on its usefulness.

      community Testosterone and hair loss seeming irrelevance

      in Research/Science  81 upvotes 1 year ago
      The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.

      community Losing Hair on Dutasteride? You might have LPP

      in Research/Science  93 upvotes 3 days ago
      Men with hair loss might have lichen planopilaris (LPP), which can mimic androgenetic alopecia, leading to misdiagnosis and ineffective treatment with finasteride or dutasteride. Proper diagnosis, including biopsies, is crucial to distinguish between androgenetic alopecia and conditions like LPP.

      community C’est terrible - at my wits end

      in Female  450 upvotes 1 year ago
      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

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