Clinical symptoms of hyperandrogenic women diagnosed with COVID‐19

    Flavio Cadegiani, Rachel Lim, Andy Goren, J. Philip McCoy, Mirna Šitum, Maja Kovacevic, Sergio Vañó Galván, Rodney Sinclair, Antonella Tosti, Carlos Gustavo Wambier
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    TLDR Women with high androgen levels may have more severe COVID-19 symptoms.
    The study investigated the severity of COVID-19 symptoms in hyperandrogenic women, who have elevated androgen levels, often due to conditions like PCOS. It involved 233 SARS-CoV-2 positive women, with 56 being hyperandrogenic and 177 non-hyperandrogenic. After matching for age and BMI, 56 matched pairs were analyzed. Results showed that hyperandrogenic women had a significantly higher incidence of several COVID-19 symptoms, suggesting they may be at increased risk for severe symptoms. The study highlighted the importance of further research and awareness of hyperandrogenism's symptoms to identify high-risk individuals, but it also noted limitations such as a small sample size and the possibility of underdiagnosed hyperandrogenism.
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