Changes in the proteomic profile of adipose tissue-derived mesenchymal stem cells during passages

    January 2012 in “ Proteome Science ”
    Emanuele Capra, Riccardo Beretta, Valentina Parazzi, Mariele Viganò, Lorenza Lazzari, Antonella Baldi, Rosaria Giordano
    TLDR Adipose stem cells show common protein changes as they grow, especially involving S100A6.
    The study identified that adipose tissue-derived mesenchymal stem cells (AD-MSC) from different donors exhibited common variations, particularly noting the presence of the protein S100A6, which is associated with cell proliferation and culture conditions. These findings supported the hypothesis that there were common proteomic changes during the expansion of MSCs, providing valuable insights into the molecular mechanisms involved in MSC expansion.
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