Cellular and Immunological Aspects of Basal Cell Carcinoma

The document discussed the cellular and immunological aspects of basal cell carcinoma (BCC), a type of non-melanoma skin cancer (NMSC) that accounted for approximately 77% of all skin cancers. The skin, comprising the dermis and epidermis, contains various cell types, including keratinocytes, melanocytes, Langerhans cells, and Merkel cells, each playing distinct roles in skin function and protection. Tumors can develop from these cells due to mutations caused by carcinogens like UV radiation. The incidence of skin cancer, including BCC, was noted to be increasing globally, prompting efforts to understand its etiology and improve clinical management.