Biochemical Factors Influencing Familial Hirsutism in the Southern Region of KPK

January 2025 in “ Journal of medical & health sciences review. ”

Abdus Sami, Muhammad Zeeshan, Aqeem ul hayat khan, Hafiza Ramla Tanveer, Syeda Hijab Fatima, Umaira Sadiq, Mueed Hanzla, Muhammad Javed, Abdus Sami, Muhammad Zeeshan, Aqeem ul hayat khan, Hafiza Ramla Tanveer, Syeda Hijab Fatima, Umaira Sadiq, Mueed Hanzla, Muhammad Javed

hirsutism androgen levels insulin resistance hormonal imbalances genetic predisposition

TLDR Hormonal imbalances and genetics are key in familial hirsutism.

The study investigates the biochemical factors contributing to familial hirsutism in the southern region of Khyber Pakhtunkhwa, Pakistan, focusing on women with a familial history of the condition. The research involved a cross-sectional analysis assessing androgen levels, insulin resistance, and hormonal profiles. Results showed that affected individuals had increased androgen levels and insulin resistance compared to a control group. A significant hereditary pattern was identified, indicating that genetic predisposition and hormonal imbalances are crucial in the occurrence of familial hirsutism in this community. Understanding these factors could aid in developing targeted treatments and improving management strategies for those affected. Further research is recommended to explore the genetic pathways and potential environmental influences.

View this study on jmhsr.com →

Discuss this study in the Community →

Related Community Posts Join

6 / 29 results

community Does low HGH leading to hairloss?

in Research/Science 12 upvotes 2 years ago

The user experiencing diffuse hair loss is using various treatments including RU58841, finasteride, minoxidil with tretinoin, anti-hair loss shampoo, and microneedling, and is considering adding peptides TB500, BPC157, and GHK-Cu. They have low growth hormone levels and are questioning its impact on hair loss, while another user suggests androgenic alopecia and androgens are likely the main cause of hair loss.

community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

in Female 55 upvotes 2 years ago

A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

community Spironolactone for 11 years, finasteride for almost 5 years, started oral minoxidil in November 😢 ended oral contraceptive in Dec.

in Progress Pictures 224 upvotes 1 year ago

A user shared their 11-year experience with spironolactone and nearly 5 years with finasteride for hair loss, recently adding oral minoxidil and stopping birth control. Various treatments were discussed, including organic options, checking for underlying health issues, considering dutasteride, and the potential role of progesterone in hair loss.

community My Experience With Finasteride

in Research/Science 20 upvotes 3 years ago

A user shared their experience with Finasteride for hair loss, noting a significant reduction in DHT levels and a complete loss of libido without other side effects. Another user agreed, discussing the negative impact on sexual drive and criticizing the community's attitude towards discussing side effects.

community Finally seeing a modest gain after over 1 year on fin and 3 months on minox. I actually have my part returning!

in Progress Pictures 808 upvotes 4 years ago

User sees modest hair gain after 1 year on finasteride and 3 months on minoxidil. Others offer support and share experiences with hair loss treatments.

community Scalp tension and thickness of the galea aponeurotica, inflammation and potential treatment pathways

in Research/Science 3 years ago

Scalp tension potentially affecting hair loss, and potential treatments for male pattern baldness such as Minoxidil, Finasteride and RU58841. Evidence from a study was discussed which suggests that the cause of MPB lies within the follicle itself and is not dependent on its surrounding environment.

Similar Research

5 / 1000+ results

Evaluating the Hormonal and Biochemical Markers in Women with Polycystic Ovarian Syndrome in Missan Province

research The Role of MicroRNA, Long Non-Coding RNA, and Circular RNA in the Pathogenesis of Polycystic Ovary Syndrome: A Literature Review

1 citations , January 2024 in “International journal of molecular sciences”

MicroRNAs could be key biomarkers and therapeutic targets for PCOS.

research A Study on Understanding and Managing Polycystic Ovary Syndrome in Adolescent Girls Aged 17-21 with Homeopathic Remedies

January 2023 in “International journal of homoeopathic sciences”

Homeopathic remedies can help manage PCOS symptoms in girls aged 17-21.