Biochemical Factors Influencing Familial Hirsutism in the Southern Region of KPK

January 2025 in “ Journal of medical & health sciences review. ”

Abdus Sami, Muhammad Zeeshan, Aqeem ul hayat khan, Hafiza Ramla Tanveer, Syeda Hijab Fatima, Umaira Sadiq, Mueed Hanzla, Muhammad Javed, Abdus Sami, Muhammad Zeeshan, Aqeem ul hayat khan, Hafiza Ramla Tanveer, Syeda Hijab Fatima, Umaira Sadiq, Mueed Hanzla, Muhammad Javed

hirsutism androgen levels insulin resistance hormonal imbalances genetic predisposition

TLDR Hormonal imbalances and genetics are key in familial hirsutism.

The study investigates the biochemical factors contributing to familial hirsutism in the southern region of Khyber Pakhtunkhwa, Pakistan, focusing on women with a familial history of the condition. The research involved a cross-sectional analysis assessing androgen levels, insulin resistance, and hormonal profiles. Results showed that affected individuals had increased androgen levels and insulin resistance compared to a control group. A significant hereditary pattern was identified, indicating that genetic predisposition and hormonal imbalances are crucial in the occurrence of familial hirsutism in this community. Understanding these factors could aid in developing targeted treatments and improving management strategies for those affected. Further research is recommended to explore the genetic pathways and potential environmental influences.

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