Evaluation of Baricitinib in Pediatric Patients With Alopecia Areata

    March 2025
    CJ Moreno Perez, Carlota Mestres Gonzalvo, Cristina Latre Gorbe, Carlos Gerardo Vargas Torres, Magdalena Adrados, Alba Casaldàliga Torrecillas
    From the encyclopedia
    Baricitinib →

    JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

    Alopecia Areata →

    autoimmune disorder causing patchy hair loss

    Studysummary This study retrospectively evaluated the effectiveness of off-label baricitinib in children with severe alopecia areata and found that 50% achieved treatment goals, though psychological effects were noted and laboratory abnormalities occurred in 42.86% of patients.
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