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    Clinical Benefits of Baricitinib Therapy for Severe Alopecia Areata

    November 2023 in “ Dermatology and Therapy ”
    Maryanne M. Senna, Oh Sang Kwon, Bianca Maria Piraccini … Brett King
    Studysummary This study found that treatment with baricitinib 4 mg over 52 weeks led to clinically meaningful regrowth of eyebrows and eyelashes in patients with alopecia areata, even without complete scalp hair regrowth.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 12

    1. Scalp Hair Regrowth Is Associated With Improvements in Health-Related Quality of Life and Psychological Symptoms in Patients With Severe Alopecia Areata: Results From Two Randomized Controlled Trials Journal of dermatological treatment · 2023
    2. Efficacy and Safety of Baricitinib in Patients with Severe Alopecia Areata Over 52 Weeks in Phase III Trials American Journal of Clinical Dermatology · 2023
    3. Integrated Safety Analysis of Baricitinib in Adults With Severe Alopecia Areata From Two Randomized Clinical Trials British journal of dermatology/British journal of dermatology, Supplement · 2022
    4. Two Phase 3 Trials of Baricitinib for Alopecia Areata The New England Journal of Medicine · 2022
    5. ‘You Lose Your Hair, What’s the Big Deal?’ I Was So Embarrassed, I Was So Self-Conscious, I Was So Depressed: A Qualitative Interview Study to Understand the Psychosocial Burden of Alopecia Areata Journal of Patient-Reported Outcomes · 2020
    6. Development of Clinician-Reported Outcome and Patient-Reported Outcome Measures for Eyebrow, Eyelash, and Nail Assessment in Alopecia Areata American Journal of Clinical Dermatology · 2020
    7. The Alopecia Areata Investigator Global Assessment Scale: A Measure for Evaluating Clinically Meaningful Success in Clinical Trials British Journal of Dermatology · 2020
    8. Response to Tofacitinib Therapy of Eyebrows and Eyelashes in Alopecia Areata Journal of the American Academy of Dermatology · 2018
    9. Spontaneous Hair Regrowth in Eight Patients with Severe Alopecia Areata Australasian journal of dermatology · 2018
    10. Alopecia Areata: Treatment Options and Efficacy Journal of the American Academy of Dermatology · 2017
    11. Health-Related Quality of Life Among Patients With Alopecia Areata: A Systematic Review Journal of The American Academy of Dermatology · 2016
    12. S1 Guideline for Diagnostic Evaluation in Androgenetic Alopecia in Men, Women, and Adolescents British Journal of Dermatology · 2010

    Related research 2

    1. Baseline Distribution of Eyebrow and Eyelash Loss by Severity of Scalp Hair Loss in Phase 3 Trials of Baricitinib for Alopecia Areata Journal of The American Academy of Dermatology · 2023
    2. A Technique for Reconstruction of Eyebrows and Eyelashes Seminars in Plastic Surgery · 2005