Association between Vitamin D Deficiency and Psoriasis: A Case-Control Study

The document discusses a case-control study conducted in Saudi Arabia involving 68 psoriasis patients and 68 control patients, which found no significant difference in serum 25-hydroxycalciferol (25(OH)D) levels between the two groups, suggesting no association between vitamin D deficiency and psoriasis. This finding is consistent with some previous research, such as the study by Wilson et al. However, other studies cited in the document, including those by Gisondi et al. and Orgaz-Molina et al., did find lower vitamin D levels in psoriasis patients, indicating a potential link. The document also mentions that Narrowband ultraviolet B (NB-UVB) therapy can increase 25(OH)D levels and improve psoriasis symptoms. The study concluded that more research with larger sample sizes is needed to clarify the relationship between vitamin D deficiency and psoriasis. Overall, the document presents mixed results from various studies on this topic.