Antioxidants and Long Covid

    October 2022
    Patrick Chambers
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    Studysummary This article discusses the complex relationship of Long Covid symptoms with multiple conditions and systems, emphasizing oxidative stress and various physiological pathways, but reports no new clinical results.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    The article "Antioxidants and Long Covid" explores the overlap of Long Covid symptoms with other chronic conditions like ME/CFS, FM, EBV, CMV, CIRS, MCAS, POTS, and post-viral fatigue syndrome, attributing these to oxidative stress and an imbalance in calcium and magnesium levels. It discusses the roles of TGF-β, IFN-γ, the RAS, and the KKS in these conditions, and provides technical explanations for phenomena such as the renin aldosterone paradox in POTS and the Warburg effect. The paper emphasizes the importance of the gut-brain axis, particularly the role of GABA and butyrates from beneficial gut bacteria, and highlights the significance of heart rate variability as an indicator of the gut-brain-heart/lung axis. A comprehensive approach to managing Long Covid and related chronic fatigue diseases is suggested.
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