Androgenetic Alopecia Updates: Pathophysiology, Diagnosis and Treatment

July 2023 in “ International journal of dermatology, venereology and leprosy sciences ”

Ahmad Akira Omar Farouk, Lamia Hamouda Elgarhy, Sherief Abd-Elsalam, Mohamed Katary, Fatma Abd El Ghafar Abd Rabo

androgenetic alopecia AGA androgens hair follicles endocrine variables genetic predisposition epithelial cells androgen-sensitive regions medical treatments surgical treatments light-based treatments hair loss hormones genetics skin cells sensitive areas medications surgery light therapy

TLDR New treatments are being explored to slow or reverse hereditary hair loss.

Androgenetic alopecia (AGA) is a hereditary disorder where hair follicles are sensitive to androgens. The progression and manifestations of AGA depend on the relationship between endocrine variables and genetic predisposition. The disorder is characterized by a gradual reduction in the size of hair follicles due to the influence of androgens on genetically predisposed epithelial cells of hair follicles in androgen-sensitive regions. There are various medical, surgical, and light-based treatments available to slow or reverse AGA's progression, with some being relatively new and still under exploration.

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