A Link Between Androgenetic Alopecia and Aging

The research paper explores the connection between androgenetic alopecia and aging, highlighting that androgenetic alopecia is the most common form of hair thinning. The study identifies several contributing factors to its development, including inflammation, oxidative stress, hormones, environmental influences, and genetics. As people age, oxidative stress and levels of reactive oxygen and nitrogen species increase, leading to the deterioration of organ and tissue function. The study uses nicotinamide adenine dinucleotide (NAD) and elastin as indicators of aging to establish a link between androgenetic alopecia and aging. The findings suggest a strong interplay between chronic inflammation, metabolic dysregulation, and elevated oxidation in the context of aging and androgenetic alopecia.