An Overview of Biopolymeric Electrospun Nanofibers Based on Polysaccharides for Wound Healing Management

The document reviewed the use of biopolymeric electrospun nanofibers (eNFs) based on polysaccharides for wound healing management. These nanofibers were noted for their ability to mimic the extracellular matrix, promoting cell adhesion and proliferation, and their porous nature allowing nutrient exchange and preventing bacterial contamination. Polysaccharides like chitosan, alginate, and cellulose were highlighted for their biocompatibility, biodegradability, and potential antimicrobial properties. The review emphasized the advantages of eNFs over traditional dressings, such as maintaining a moist environment and allowing gas exchange. Various studies demonstrated the effectiveness of these eNFs in promoting wound healing, reducing inflammation, and providing antibacterial effects, with specific formulations showing promising results in in vivo studies. The document also discussed the challenges in transitioning from laboratory to clinical applications and the need for multidisciplinary collaboration to address limitations in current wound dressings.