In their review, the authors discussed the increasing issue of allergies to hair products, highlighting common allergens such as hair dyes and topical minoxidil, and outlined diagnostic methods and alternatives for those affected, particularly addressing higher risks among hairdressers due to professional exposure.
December 2025 in “Applied and Computational Engineering” In this study, researchers explored the potential allergenicity and harmful effects of hair dyes, noting that adverse effects such as sensitization and potential carcinogenicity are not inevitable and can vary based on individual physiological differences.
February 2026 in “PubMed” This study reported that para-phenylenediamine and toluene-2,5-diamine are the main sensitizers in hair dye-related allergic contact dermatitis, with significant cross-reactivity to several other compounds.
July 2026 in “International Journal of Applied Pharmaceutics” This review discusses the dermatological and systemic adverse effects of hair dye use, particularly focusing on the common allergen para-phenylenediamine, and reports no new clinical data.
January 2004 in “Side effects of drugs annual” Certain skin drugs and topical agents, including some natural extracts and fragrances, can cause allergic reactions. Some hair dyes and extensions, as well as minoxidil, a hair growth treatment, can also cause allergies. Botulinum toxin A can effectively reduce sweat but may have temporary side effects.