Recent Advancements in Wound Management: Tailoring Superwettable Bio-Interfaces

Recent advancements in wound management have focused on superwettable bio-interfaces, which effectively control biofluids like blood and exudates. Traditional dressings often cause secondary injuries and blood loss due to their hydrophilic nature. Superwettable materials, such as Janus dressings with superhydrophilic and superhydrophobic properties, have shown to reduce blood loss by over 50% in rat models compared to conventional gauzes. These materials expedite clotting, prevent blood penetration, and reduce bacterial infection, significantly improving wound care. The review encourages further design and application of these materials to enhance wound healing, fluid management, and tissue regeneration.