Acute Fish Liver Intoxication: Report of Three Cases

The document reported three cases of acute fish liver intoxication after consuming the liver of the grouper fish Cephalopholis boenak. The patients experienced symptoms such as dizziness, headache, blurred vision, nausea, vomiting, fever, and skin desquamation, which were similar to acute hypervitaminosis A due to high vitamin A content in the fish liver. One patient exhibited severe symptoms, including high fever, generalized pain, and skin vesicles. Treatment was supportive, but one patient developed hair loss and skin peeling on palms and soles during follow-up. Ethanol might have exacerbated the intoxication. This condition was rare, especially in subtropical regions.