Acitretin: A Good Treatment Option for Hypertrophic Lichen Planus
January 2016
in “
Indian journal of drugs in dermatology
”
Studysummary This case report describes a 48-year-old male with severe, itchy hypertrophic lichen planus who showed a 90% improvement in lesions following 4 months of treatment with oral acitretin, with no recurrence 6 months posttreatment. Our plain-language summary of this paper — not a Tressless recommendation.
A 48-year-old male with a 15-year history of hypertrophic lichen planus (HLP) experienced significant improvement after being treated with oral acitretin. Previous treatments provided only temporary relief. Acitretin 25 mg twice daily, along with oral hydroxyzine and topical treatments, led to a 30-40% improvement in lesions and reduced itching within 2 weeks. After 2 months, there was a 90% improvement, and the treatment was well-tolerated with minor side effects. No recurrence was reported up to 6 months post-treatment, suggesting acitretin as a viable option for severe HLP cases.