[A systemic lupus erythematosus patient with multiple aseptic bone necroses, thrombosis of superior mesenteric artery and anti-phospholipid antibody].

A 38-year-old woman with a long history of systemic lupus erythematosus (SLE) presented with epigastric pain and fever, having been diagnosed with SLE 22 years prior due to symptoms like Raynaud's phenomenon and hair loss. She had previously experienced multiple aseptic bone necroses and underwent bilateral femoral head arthroplasty. Upon admission, she was found to have thrombosis in the superior mesenteric artery (SMA) and other arteries, with positive anti-cardiolipin and lupus anticoagulant antibodies, but normal anti-DNA antibody and complement levels. Despite conservative treatment, surgical resection of the small intestine and right colon was necessary. The case highlighted the association between anti-phospholipid antibodies and thrombosis, as well as the etiology of multiple bone necroses in SLE patients.