A Novel Framework for Integrative Hair Longevity Management

The document presents a novel framework for managing hair longevity by shifting focus from treating visible hair loss to preserving follicular health proactively. It highlights that hair ageing is a multifactorial process involving structural and functional deterioration of hair follicles, leading to reduced hair quality. The study synthesizes 102 articles to establish a framework identifying nine hallmarks of hair ageing, influenced by genetic, hormonal, environmental, and lifestyle factors. The proposed integrative approach to managing androgenetic alopecia (AGA) includes pharmacological treatments, cosmetic formulations, nutritional supplements, medical devices, and lifestyle strategies. This approach emphasizes prevention, early intervention, and the development of innovative formulations to support lifelong scalp and hair health.