TLDR RU58841 significantly increases hair growth rate and initiates more hair cycles, but doesn't affect hair thickness, suggesting it could be a new treatment for baldness.
In 1997, a study involving 20 scalp grafts from balding men was conducted to investigate the effects of RU58841, a non-steroidal antiandrogen, on human hair growth. These grafts were maintained on testosterone-conditioned nude mice for 8 months and treated with either RU58841 or a control solution. The study found that grafts treated with RU58841 had a significantly higher linear hair growth rate and a higher percentage of follicles initiating a second hair cycle compared to the control grafts. However, RU58841 did not affect hair diameter. These results suggested that RU58841 could potentially be a new treatment for androgen-dependent alopecia.View this study on academic.oup.com →
Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.
RU 58841 may treat acne, hair loss, and excessive hair growth.
Minoxidil, originally a blood pressure medication, is effective in treating hair loss in men and women, with different strengths recommended for each.
Hair loss needs more research for better treatments.
RU58841 significantly increases hair growth rate and initiates more hair cycles, but doesn't affect hair thickness, suggesting it could be a new treatment for baldness.
Male-pattern baldness is a natural process with unclear causes, and while Minoxidil can help, the results often aren't satisfactory.