A Controlled Study of the Effects of RU58841, a Non-Steroidal Antiandrogen, on Human Hair Production by Balding Scalp Grafts Maintained on Testosterone-Conditioned Nude Mice

    November 1997 in “ British Journal of Dermatology ”
    B. de Brouwer, C. Tételin, T. Leroy … D. Van Neste
    Studysummary This study found that the non-steroidal antiandrogen RU58841 increased hair growth rates and promoted hair cycle initiation in balding human scalp grafts on testosterone-conditioned nude mice, indicating a positive effect on hair growth.
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    Research cited in this study 3

    1. Preliminary Pharmacokinetics and Metabolism of Novel Non-Steroidal Antiandrogens in the Rat: Relation of Their Systemic Activity to the Formation of a Common Metabolite The Journal of Steroid Biochemistry and Molecular Biology · 1994
    2. RU 58841, A New Specific Topical Antiandrogen: A Candidate of Choice for the Treatment of Acne, Androgenetic Alopecia, and Hirsutism The Journal of Steroid Biochemistry and Molecular Biology · 1994
    3. Reduced Linear Hair Growth Rates of Vellus and Terminal Hairs Produced by Human Balding Scalp Grafted onto Nude Mice Annals of the New York Academy of Sciences · 1991

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    3. A Controlled Study of the Effects of RU58841, a Non-Steroidal Antiandrogen, on Human Hair Production by Balding Scalp Grafts Maintained on Testosterone-Conditioned Nude Mice British Journal of Dermatology · 1997
    4. Clinical Updates in Hair Dermatologic Clinics · 1997
    5. Androgenetic Alopecia in Males: Recent Developments PubMed · 1989