A complete guide to human microbiomes: Body niches, transmission, development, dysbiosis, and restoration

The document provided a comprehensive overview of the human microbiome, emphasizing its critical role in human health as a co-evolved system of microbial communities. It highlighted how modern lifestyles have led to the extinction of indigenous microbes, contributing to various diseases and epidemics. The review detailed the different human body niches and their dominant microbial taxa, discussed the effects of urbanization on microbial homeostasis, and explored efforts to restore and preserve beneficial microbes. The guide aimed to serve as a valuable resource for understanding the human holobiont and the importance of maintaining microbial diversity.