Management of Tinea Capitis in Childhood
July 2010
in “
Clinical, cosmetic and investigational dermatology
”
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Studysummary This review discusses systemic antifungal treatments for tinea capitis in children, noting that newer agents like terbinafine and itraconazole require shorter courses than the traditional griseofulvin, but may be more costly.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
Tinea capitis (TC) is a dermatophyte infection prevalent in prepubertal children, primarily caused by Trichophyton and Microsporum genera, with T. tonsurans being the most common pathogen and M. canis second, especially in the Mediterranean region where pets are significant carriers. Systemic treatment is necessary as topical agents cannot reach the deepest part of the hair follicle. Griseofulvin has been the standard systemic therapy since the late 1950s due to its effectiveness against dermatophytes and long-term safety, but its main drawback is the lengthy treatment period which can affect compliance. Newer oral antifungals like terbinafine, itraconazole, ketokonazole, and fluconazole have similar efficacy and potential side effects as griseofulvin for TC caused by Trichophyton species but require shorter treatment times, although they may be more costly.
