Dermatologic Implications of GLP-1 Receptor Agonist Medications: A Comprehensive Review

    February 2025 in “ Skin Appendage Disorders ”
    Olivia Burke, Sunday Agba Bisong, David Alvarez Cespedes, Antonellá Tosti
    TLDR GLP-1 receptor agonists can cause skin reactions, facial fat loss, and hair loss, but may help with wound healing and skin conditions.
    Glucagon-like peptide-1 receptor agonists (GLP-1RAs), used for managing type 2 diabetes and obesity, have notable dermatologic effects, including injection-site reactions, hypersensitivity, urticaria, and bullous pemphigoid. "Ozempic Face," characterized by facial fat loss, and hair loss in the form of telogen effluvium, are linked to rapid weight loss from GLP-1RA use. These medications also show potential in enhancing wound healing and treating inflammatory skin conditions like psoriasis. As GLP-1RAs become more common for weight management, clinicians should monitor for dermatologic side effects and consider dermatologic consultations. Further research is needed to balance therapeutic benefits with minimizing adverse skin outcomes.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 31 results

      community Will Pp405 be the Ozempic of bald Guys

      in Research/Science  104 upvotes 1 week ago
      PP405 is being discussed as a potential hair loss treatment, possibly more effective than minoxidil. There are concerns about its effectiveness and product contamination, but some users report early signs of hair regrowth.

      community Did UCLA Just Cure Baldness? Check this Out!

      in Research/Science  972 upvotes 1 year ago
      UCLA's PP405 shows promise in reactivating dormant hair follicles for hair loss treatment but is still in clinical trials. Minoxidil and finasteride remain common treatments until PP405 becomes available.

      community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

      in Female  53 upvotes 2 years ago
      A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

      community He used Dutasteride for 20 years. Interview

      in Treatment  111 upvotes 1 year ago
      Dutasteride has been used for 20 years with some hair thickness improvement but no dramatic regrowth. The user also experimented with minoxidil, tretinoin, and peptides like BPC 157 for potential benefits in hair density and quality.

    Similar Research

    5 / 221 results