Successful Treatment of Steroid-Immunosuppressant Resistant Polymyositis with Immunoadsorption
November 1991
in “
PubMed
”
Studysummary This report describes a case of polymyositis that was resistant to steroids and immunosuppressants but showed improvement with immunoadsorption therapy.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
The document reported a case of a 46-year-old man with "steroid and immunosuppressant-resistant" polymyositis who was successfully treated with immunoadsorption. The patient experienced muscle weakness and pain, Raynaud's phenomenon, and elevated body temperature. Despite treatment with high-dose methylprednisolone, prednisolone, and azathioprine, his condition worsened, leading to severe muscle weakness and inability to walk. A muscle biopsy confirmed polymyositis. Upon transfer to Shinshu University Hospital, the patient exhibited additional symptoms such as hair loss and cervical lymphadenopathy. Immunoadsorption was employed as a treatment, which proved successful in managing his condition.
