Topical Cyclosporine in Alopecia Areata

    February 1987 in “ Archives of Dermatology
    Aurora Parodi, Alfredo Rebora
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    Alopecia Areata →

    autoimmune disorder causing patchy hair loss

    Studysummary This case report describes the topical application of cyclosporine in a man with alopecia universalis, which showed hair regrowth after 10 months of daily use, except where limited by a congenital nevus.
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    A 23-year-old man with alopecia universalis, who previously experienced hair regrowth with oral corticosteroids followed by hair loss upon cessation, was treated with a topical cyclosporine lotion. The treatment involved daily application of a solution containing 250 mg of cyclosporine in a mixture of isopropyl alcohol, propylene glycol, and distilled water. Despite no initial hair growth observed by September 1985, continued application led to noticeable hair regrowth by March 1986, except on a congenital nevus where the lotion was not applied.
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