TLDR 5alpha-reductase inhibitors help treat hair loss and prostate issues but may cause sexual side effects.
The document provided an update on the use of 5alpha-reductase inhibitors, which were used primarily for the treatment of conditions like benign prostatic hyperplasia and androgenetic alopecia. These inhibitors worked by blocking the conversion of testosterone to dihydrotestosterone (DHT), a hormone linked to hair loss and prostate growth. The review discussed the efficacy and safety profiles of these drugs, highlighting their role in reducing symptoms and slowing disease progression. It also addressed potential side effects, such as sexual dysfunction, and emphasized the importance of patient selection and monitoring during treatment.
1 citations
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June 2021 in “Singapore Medical Journal” Dutasteride and finasteride can help increase hair growth gene expression but need further improvement.
19 citations
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April 2020 in “Dermatologic Therapy” Dutasteride works better than finasteride for hair loss, with both being safe to use.
January 2018 in “Surgical and Cosmetic Dermatology” 5-alpha reductase inhibitors like finasteride and dutasteride are effective for treating enlarged prostate and male pattern hair loss.
8 citations
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January 2016 in “Indian Journal of Pharmacology” Finasteride and dutasteride can cause severe, lasting side effects.
1 citations
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January 2012 in “Daehan namseong gwahag hoeji” Dutasteride is more effective than Finasteride in reducing prostate size and PSA levels, but both drugs have similar side effects.
47 citations
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January 2003 in “Current opinion in urology” A new drug, dutasteride, is at least as effective as the older drug, finasteride, for treating enlarged prostate and may have additional uses.
