I am going to reduce finasteride to half the dose (0.5 mg) and I have several questions 8/21/2025
A 34-year-old man plans to reduce his finasteride dose from 1 mg to 0.5 mg due to negative side effects like hormonal imbalances and seeks advice on managing these effects and potential alternatives. Suggestions include considering dutasteride as an alternative and noting that a new equilibrium with a reduced dose may take about two weeks.
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community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?
Topical dutasteride is suggested as a low side-effect treatment for hair loss, with a proposed dose of 0.025% 1ml/day. It is considered better than finasteride due to its even inhibition of DHT isoforms and lower systemic absorption.
community I cannot sleep anymore, what should I do
Finasteride may cause sleep disturbances, with some users experiencing insomnia. Reducing the dosage, switching brands, or trying Dutasteride might help.
community Husband (35) is thinning on top, he doesn't know yet. Trying to research so he won't feel so lost or upset when I tell him. Help a girl out?
A woman is concerned about her husband's hair thinning and researches treatments like finasteride and minoxidil. He decides against medication due to potential side effects and plans to shave his head if necessary.
community Who here has maintained with finasteride for decades?
People have been using finasteride for 10 to 20+ years to maintain their hairline, with many reporting success and no significant side effects. Some users have combined finasteride with minoxidil for better results, and a few have switched to dutasteride or added hair transplants when finasteride was less effective.
community Can we stop fear mongering with finasteride
Finasteride is effective for hair loss but can cause sexual dysfunction and mental health issues in some users, leading to a polarized debate on its risks. Some switch to alternatives like Dutasteride or topical treatments to avoid side effects.
community Iām considering stopping finasteride
The user is considering stopping finasteride due to depression, anxiety, and difficulty building muscle, despite its effectiveness in stopping hair loss. Suggestions include reducing the dose, switching to topical solutions, or consulting a doctor for alternatives like dutasteride or RU58841.
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research Signal Detection of Depression and Suicidality Associated with Finasteride and Dutasteride: Updated Pharmacovigilance Evidence and Recommendations for Comprehensive Psychiatric Assessment
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This study found that eyelash loss, facial papules, and body hair involvement were linked to severe frontal fibrosing alopecia, and antiandrogens were the most effective treatment.
research 5Ī±-Reductase inhibitors alter steroid metabolism and may contribute to insulin resistance, diabetes, metabolic syndrome and vascular disease: a medical hypothesis
This report advances the hypothesis that finasteride and dutasteride inhibit 5Ī±-reductase activities, potentially altering steroid metabolism and increasing the risk of insulin resistance, diabetes, and vascular disease.
research Antiandrogens and Androgen Inhibitors
This source outlines various antiandrogen and androgen inhibitor drugs used to treat cutaneous disorders of hyperandrogenism, detailing their mechanisms, uses, dosages, and side effects, with emphasis on spironolactone, finasteride, dutasteride, and oral contraceptives.