May 2021 in “Journal of Investigative Dermatology” A trial showed that a new treatment is safe and effective for male pattern baldness, with most participants growing new hair.
34 citations
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December 1991 in “Annals of the New York Academy of Sciences” The conclusion is that small hair follicles cause baldness in macaques, and treatments like antiandrogens and minoxidil can prevent hair loss and promote regrowth.
234 citations
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April 2000 in “Gene” Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.
January 2019 New treatments for hair loss show promise, including plasma, stem cells, and hair-stimulating complexes, but more research is needed to fully understand them.
2 citations
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November 1987 in “Archives of Dermatology” Lotions release minoxidil better than creams, with a recommended mix of propylene glycol, water, and ethanol improving effectiveness.
11 citations
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August 2013 in “Facial Plastic Surgery Clinics of North America” New cell-based therapies may improve hair loss treatments in the future.
8 citations
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June 2011 in “Nature Biotechnology” Stem cell treatments can potentially treat baldness, with one trial showing hair growth after injecting a hair-stimulating complex, and no safety issues were reported.
4 citations
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April 2019 in “Annals of Dermatology” Higher levels of MiR-92a-1-5p and miR-328-3p found in female hair loss patients.
1 citations
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May 2011 in “Journal of Obstetrics and Gynaecology” Hair loss in postmenopausal women due to ovarian hyperthecosis is rare, but removing the ovaries can significantly improve the condition.
May 2018 in “Journal of Investigative Dermatology” The study found that p63 needs signals from morphogens to help skin cells differentiate properly.
May 2018 in “Journal of Investigative Dermatology” DPP4 is important for scarring and skin regeneration, and managing its activity could improve skin healing treatments.
1054 citations
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February 1998 in “The New England Journal of Medicine” Finasteride reduces urinary issues and surgery need in men with enlarged prostates by over 50%.
401 citations
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January 2013 in “Postepy Dermatologii I Alergologii” The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.
205 citations
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March 2012 in “Science Translational Medicine” PGD2 stops hair growth and is higher in bald men with AGA.
187 citations
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January 1994 in “The New England Journal of Medicine” Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.
172 citations
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January 2005 in “Journal of The American Academy of Dermatology” Demodicosis is common and often missed, needing more recognition and treatment in skin care.
163 citations
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April 1953 in “Acta radiologica” Radiation therapy with a higher dose for the brain improves survival in cerebellar medulloblastoma.
160 citations
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June 2012 in “Journal of Cellular and Molecular Medicine” Telocytes might help with skin repair and regeneration.
137 citations
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June 2005 in “Climacteric” Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.
116 citations
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August 2010 in “Nature” Scientists turned rat thymus cells into stem cells that can help repair skin and hair.
112 citations
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January 2014 in “Molecular and cellular therapies” Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
110 citations
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August 2016 in “Drugs” Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.
106 citations
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March 2014 in “BioEssays” We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.
89 citations
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September 2010 in “Annual Review of Genomics and Human Genetics” The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.
86 citations
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March 1993 in “Toxicology and Applied Pharmacology” Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.
83 citations
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May 2015 in “World Journal of Stem Cells” Hair follicle regeneration needs special conditions and young cells.
65 citations
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February 2015 in “Neuro-Oncology” Alisertib was found to be an effective and tolerable treatment for children with recurrent brain tumors.
62 citations
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July 1993 in “Journal of Investigative Dermatology” Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.
57 citations
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March 2018 in “International Journal of Molecular Sciences” The extracellular matrix is crucial for controlling skin stem cell behavior and health.
55 citations
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October 1992 in “Archives of Dermatology” Loose Anagen Hair Syndrome is a hereditary condition causing hair loss in children due to abnormal hair follicles.