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New in community
- Featured Community Post
Research Backed Dutasteride Simulator (Serum/scalp DHT included for all doses)
A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.
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6ish months into treatment. Norwood 69 progress
Progress Pictures The user started using Minoxidil and finasteride for hair loss, noticing some progress after six months, despite a recent shedding phase. They also use derma stamping and various topical products, though their effectiveness is uncertain. -
6 Month Update - (3 Month of Finasteride)
Progress Pictures The user experienced positive hair regrowth after 6 months of treatment, using topical minoxidil and finasteride, with no significant side effects. They also improved their diet and exercise routine, and are considering dermarolling if progress stalls. -
”Why are we not funding this?” - Peter Griffin
Finasteride/Dutasteride Topical finasteride can reduce scalp DHT as effectively as oral finasteride with fewer systemic effects, but availability is limited. Some users make their own solutions due to limited access. -
Just a reminder not everything is about dht blockers and why vitamins are important
Progress Pictures The conversation discusses the impact of vitamins, stress reduction, and appropriate shampoo on hair health, with the original poster noting slight improvements after two months of using vitamins B5, B6, zinc, and a suitable shampoo. Many users express skepticism about the effectiveness of vitamins for hair loss unless there is a deficiency, emphasizing the importance of addressing DHT and considering 5AR inhibitors. -
Progress- 3 months, 5% Minoxidil, 0.1% Finasteride
Is this regrowth? The user experienced significant hair loss after stopping a treatment of 5% Minoxidil and 0.1% Finasteride, which they had used from December 2021 to January 2024. They resumed the treatment in April 2025, hoping for regrowth, and are considering additional treatments like transplants and steroid injections. -
1 year on fin/min. This is your reminder to power through!
Progress Pictures The user experienced significant hair regrowth after one year of using oral minoxidil (2.5mg) and oral finasteride (1mg), with no side effects except initial shedding. The user noticed thicker eyebrows and beard, and the hairline improved with baby hairs, but the hair quality differs from the rest of the head.
New Featured Research
Lnc056 Enhances Hair Follicle Stem Cells Proliferation by Binding Transcription Factor HNRNPUL1 to Up-Regulate TRIP6 Expression.
This study investigates the role of the long non-coding RNA lnc056 in the proliferation of hair follicle stem cells (HFSCs). The research found that lnc056 is expressed in the nuclei of HFSCs and promotes their proliferation by up-regulating the expression of TRIP6 through binding with the transcription factor HNRNPUL1. The study utilized various methods, including RT-qPCR and overexpression assays, to demonstrate that lnc056 enhances HFSC proliferation via the HNRNPUL1/TRIP6 axis. These findings contribute to understanding the molecular mechanisms of lncRNA in the hair follicle cycle and suggest lnc056 as a potential therapeutic target for hair loss.
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New in research
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Clinical and Trichoscopic Analysis of PRP Versus GFC for Male and Female Pattern Hair Loss
GFC improves hair quickly, while PRP offers longer-lasting benefits; using both sequentially is recommended.
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GLP-1 Receptor Agonists and Skin Health: Exploring Dermatologic Side Effects and Therapeutic Interventions
GLP-1 receptor agonists can cause skin and hair issues due to rapid weight loss, but these can be managed with proper care and treatments.
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Controlled Release of Minoxidil Through Hydrogel Cross-Linking to Treat Androgenetic Alopecia
A new method using hydrogels and microneedle patches improves minoxidil delivery for better hair growth.
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Ayurvedic Management of Indralupta with Special Reference to Alopecia Areata: A Case Report
Ayurvedic treatment successfully regrew hair in a woman with alopecia areata.
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Finasteride: Risk of Suicidality and Depression
Finasteride may increase the risk of depression and suicidal thoughts.
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Long-Term Real-World Outcomes of Baricitinib in Severe Alopecia Areata: A 104-Week Retrospective Analysis From a Single Institute
Baricitinib is effective and safe for long-term treatment of severe alopecia areata.
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Pathophysiology, Conventional Treatments, And Evidence-Based Herbal Remedies Of Hair Loss With A Systematic Review Of Controlled Clinical Trials
Herbal remedies may help with hair loss but need more research.
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Prostaglandin F2α Stimulates Growth of Human Intermediate Hair Follicles in Ex Vivo Organ Culture with Potential Clinical Relevance
Prostaglandin F2α may help treat hair loss by promoting hair growth.
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Restoration of Hair Luster via Novel Biomarker COL7A1 by Minoxidil, Caffeine, and Biotin
Minoxidil, caffeine, and biotin can improve hair shine by restoring certain genes.