[Wound-induced hair follicle neogenesis: a new perspective on hair follicles regeneration in adult mammals].
March 2020
in “PubMed”
TLDR Wound-induced hair follicle creation is a complex process in adult mammals that involves various cells and immune responses, and understanding it better could help improve skin healing strategies.
The review from 2020 explored the research progress of wound-induced hair follicle neogenesis (WIHN) in adult mammals. WIHN is a rare regeneration phenomenon in the skin of adult mammals, with multiple cell origins, including hair follicle stem cells and epithelial stem cells around the wound. The molecular mechanism of WIHN is complex and regulated by many signaling pathways. The process is also closely related to the immune response, with immunocytes and their related cytokines providing suitable conditions for this process. However, there were still many unsolved problems regarding the cellular origins and molecular mechanisms of WIHN. Further study on the mechanisms was suggested to enhance the understanding of adult mammals' hair follicle regeneration and potentially provide new strategies for functional healing of the human skin.
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