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Stefano, a 20-year-old male, experienced significant hairline shedding and thinning after using topical Minoxidil, along with rosemary/jojoba oil, biotin tablets, caffeine shampoo, and a dermaroller. He is uncertain whether to continue the treatment in hopes of regrowth or stop and potentially return to his original hair condition, while a reply suggests using finasteride or dutasteride to address the underlying cause of hair loss.

community Pumpkin seed oil for hair loss. Has anyone actually tried it? Suddenly PSO is everywhere.

in Research/Science 1 year ago

Pumpkin seed oil is a weak natural DHT inhibitor and not effective for significant hair loss. Effective treatments include finasteride, minoxidil, and other medications.

community Found a winning combo for a non/weak-responder

in Research/Science 4 upvotes 2 years ago

A user found a successful hair loss treatment using a combination of finasteride, dutasteride, minoxidil, and RU58841. They plan to switch to a purely topical regimen with finasteride, RU58841, and minoxidil.

community Diffuse thinner with hair transplant no longer an option. Any other viable treatments I can add to my regimen?

4 upvotes 7 years ago

The user is exploring alternatives to hair transplants due to a weak donor area and is currently using finasteride, minoxidil, dermapen, low-level laser therapy, Nizoral shampoo, and a high-protein diet. They plan to switch to dutasteride and consider adding RU58841, while rejecting hair systems and considering a buzz cut.

community Does Minoxidil make you lose more hair if you stop it?

4 upvotes 5 years ago

The conversation is about someone considering using Minoxidil combined with a weak antiandrogen for hair loss, but is concerned about potential increased hair loss if they stop using Minoxidil. They are seeking others' experiences with stopping Minoxidil and the effects on their hair.

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Research

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research Cosmetic Products and Hair Health

January 2015 in “Springer eBooks”

This review discusses the transition of healthy hair to an unhealthy state due to structural and physiological disruptions, but reports no new results.

research A novel pathogenic variant of NECTIN4 gene in a child with ectodermal dysplasia-syndactyly syndrome

January 2023 in “Indian dermatology online journal”

This case report describes a novel NECTIN4 gene mutation linked to ED-syndactyly syndrome 1 in a young girl, contributing to the understanding of this rare ectodermal dysplasia.

research Molecular mechanisms of androgenetic alopecia

229 citations , August 2002 in “Experimental Gerontology”

This paper discusses key mechanisms of androgen metabolism in androgenetic alopecia and reports the effectiveness of treatments like oral finasteride and topical minoxidil, highlighting the limited success rate due to factors like follicular inflammation.

research Role of Dehydroepiandrosterone and Dehydroepiandrosterone Sulfate for the Maintenance of Axillary Hair in Women

5 citations , January 1993 in “Hormone and Metabolic Research”

This study suggests that weak adrenal androgens like dehydroepiandrosterone and dehydroepiandrosterone-sulfate may play a key role in maintaining axillary hair in women over 50, rather than testosterone.

research The effect of inhaled corticosteroids on hair cortisol

September 2018

This study found a weak negative correlation between inhaled corticosteroid dose and hair cortisol levels in children with asthma, suggesting that hair cortisol measurement may reflect adrenal function in these children.

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